Agony: contest; wrestling; severe struggling with pain and suffering.
Anguish is the reflection on evil that is already past, while
agony is a struggle with evil at the time present. It is only
used in the New Testament by Luke (22:44) to describe our Lord's
fearful struggle in Gethsemane.
The verb from which the noun "agony" is derived is used to
denote an earnest endeavour or striving, as "Strive [agonize] to
enter" (Luke 13:24); "Then would my servants fight" [agonize]
(John 18:36). Compare 1 Cor. 9:25; Col. 1:29; 4:12; 1 Tim. 6:12; 2
Tim. 4:7, where the words "striveth," "labour," "conflict,"
"fight," are the renderings of the same Greek verb.